Sentence and cancer type
Showing 1-20 of 49 items.
SentenceCancertype
Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells.pancreatic,
Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma.pancreatic,
data provide a structural basis for understanding the role of menin as a tumor suppressor protein and as an oncogenic co-factor of mixed lineage leukemia fusion proteinsleukemia,
overview of cellular functions of MEN1 in various tissues in addition to its tumor suppressor function; this review discusses roles of MEN1 in cell differentiation and signal transduction in bone and parathyroid glands [REVIEW]thyroid,
Findings indicate that MEN1 tumor suppressor gene replacement therapy can generate menin expression in pituitary tumors, and significantly reduce tumor cell proliferation.pituitary,
The tumor suppressor protein menin inhibits NF-kappaB-mediated transactivation through recruitment of Sirt1 in hepatocellular carcinoma.liver,
MEN1 is a melanoma tumor suppressor that functions by stimulating the transcription of genes involved in homologous recombination-directed DNA repair.skin,
miR-802 expression levels are increased in lung carcinoma tissues and targets the tumor suppressor menin and downregulates its expression.lung,
Tumor suppressor Menin acts as a corepressor of LXR? to inhibit hepatic lipogenesisliver,
Primary structure, gene expression and chromosomal mapping of rodent homologs of the MEN1 tumor suppressor gene.None
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation.None
Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse.None
MEN1 tumor-suppressor protein localizes to telomeres during meiosis.None
The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene.None
Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.None
menin plays an important role in the embryonic development of multiple organs in addition to its proposed role in tumor suppressionNone
Multiple tumor suppressor pathways negatively regulate telomerase.None
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain.None
Functional characterization of a promoter region in the human MEN1 tumor suppressor gene.None
Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex.None