Sentence and cancer type
Showing 21-40 of 49 items.
SentenceCancertype
the smad pathway and the tumor suppressor menin are key regulators of activin effects on PRL and Pit-1 expression, as well as on cell growth inhibitionNone
Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2.None
Direct binding of DNA by tumor suppressor menin.None
Functional interaction between tumor suppressor menin and activator of S-phase kinase.None
that regulation of cyclin-dependent kinase inhibitor transcription by cooperative interaction between menin and MLL plays a central role in menin_s activity as a tumor suppressorNone
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.None
The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.None
The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.None
analysis of menin_s role as a tumor suppressor and binding sites of Rbbp5 and MLL1None
Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583.None
Results suggest that menin and pRb function in a common pathway of tumor suppression.None
High frequencies of MEN1 gene mutations were detected in Brazilian families with MEN1, including seven new genetic mutations that are predicted to cause inactivation of the MEN1 tumour suppressor gene.None
The expression changes associated with the loss of the tumor suppressor menin provide insights into the defective organogenesis observed during early embryonic development in Men1-null mouse embryos.None
Here we show that menin, a protein previously characterized as an endocrine tumor suppressor and transcriptional regulator, controls islet growth in pregnant miceNone
Multiple Endocrine Neoplasia type 1 (MEN-1) and is caused by a germ-line mutation in MEN-1 gene encoding a tumour suppressor protein, menin.None
In vitro hematopoietic differentiation of mouse embryonic stem cells requires the tumor suppressor menin and is mediated by Hoxa9.None
The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation.None
Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma.None
The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization.None
the menin tumor suppressor protein undergoes DNA damage induced phosphorylation and participates in the DNA damage transcriptional response.None