Sentence and cancer type
Showing 1-16 of 16 items.
SentenceCancertype
the promoter activity of myeloproliferative leukemia virus oncogene is modulated by transcription through a PKC-dependent pathwayleukemia,
Oncogenic activation of MPL/thrombopoietin receptor by 17 mutations at W515: implications for myeloproliferative neoplasms. neoplasm,
Lack of c-mpl proto-oncogene transcripts and growth-stimulatory effects of thrombopoietin on human small cell lung cancer cell lines. lung,
Modulation of human c-mpl gene expression by thrombopoietin through protein kinase C. None
Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. None
The oncogene V-MPL, a putative truncated cytokine receptor which immortalizes hematopoietic progenitors. None
it was concluded that the oncogenic event in idiopathic myelofibrosis associated with the MPLW515L/K mutations probably occurs in a progenitor cell common to both myeloid and lymphoid cells, such as the pluripotent haematopoietic stem cellNone
MPL 515 and JAK2 mutation analysis in MDS presenting with a platelet count of more than 500 x 10(9)/l. None
Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2. None
Hypomethylation mediated by decreased DNMTs involves in the activation of proto-oncogene MPL in TK6 cells treated with hydroquinone. None
His(499) regulates the activation of human TpoR and provides additional protection against activating mutations, such as oncogenic Asn mutations in the TM domainNone
From the v-mpl oncogene to thrombopoietin. None
Expression of the c-mpl proto-oncogene in human hematologic malignancies. None
Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth. None
Proto-oncogene c-mpl is involved in spontaneous megakaryocytopoiesis in myeloproliferative disorders. None
Thrombopoietin and its receptor, the proto-oncogene c-mpl. None