| Our findings suggest that miR-340 may function as a novel tumor suppressor in prostate cancer | prostate, |
| MiRNA-340 acts as an anti-oncogene in endometrial carcinoma cell line RL 95-2 by inhibition of tumor cell proliferation and induction of apoptosis. | endometrial, |
| miR-340 acts as a tumor suppressor in colorectal cancer and is involved in the chemoresistance of colorectal cancer. | colorectal, |
| The results of the present study revealed that miR340 serves a tumor suppressor role by influencing the proliferation, apoptosis, migration and invasion of HCC cell lines, which may be explained by the downregulation of SKP2 by miR340. | liver, |
| This study revealed the tumor suppressive role of miR-340 in ovarian cancer cells by negative regulation of BAG3; PI3K/AKT pathway might be involved in the regulation of miR-340 and BAG3. | ovarian, |
| MiR-340 overexpression inhibited tumor growth by regulating CDK4 expression. miR-340 functions as a tumor suppressor in non small cell lung cancer (NSCLC) cells and may provide a potential target of NSCLC treatment. | lung, |
| miR-340 acts as a tumor suppressor and its downregulation in tumor tissues may contribute to the progression and metastasis of OS through a mechanism involving ROCK1 | None |
| NT5E-targeting miRNAs (miR-30b and miR-340) function as tumor suppressors | None |
| Study in squamous cell carcinoma (SCC) cells and tissues findings demonstrate the tumor suppressor role of miR-340 in SCC by directly regulating RhoA. | None |
| In myeloma, methylation-mediated silencing of miR-340 is tumor-specific, reversible, associated with inferior overall survival, and likely an early event in myelomagenesis. Moreover, miR-340 potentially exerts its tumor suppressive function via regulation of MAPK signaling and apoptotic pathways. | None |