Sentence and cancer type
Showing 1-20 of 21 items.
SentenceCancertype
the function of RON in tumors may be multidimensional, not just as a tumor suppressor or oncogene.None
Targeted expression of the receptor tyrosine kinase RON in distal lung epithelial cells results in multiple tumor formation: oncogenic potential of RON in vivo. lung,
The Ron proto-oncogene product is a phenotypic marker of renal oncocytoma. kidney,
Expression of RON Proto-oncogene in Renal Oncocytoma and Chromophobe Renal Cell Carcinoma. kidney,
The proto-oncogene, c-Cbl, which modulates ubiquitylation of RON, was increased in glia in both multiple sclerosis brains and experimental autoimmune encephalomyelitis spinal cordsbrain,
Regulation of RON tyrosine kinase-mediated invasion of breast cancer cells. breast,
RON has 2 alternative SRC-kinase-mediated modes of signaling that can contribute to oncogenic behavior in normal breast epithelial cells: an MSP-dependent increase in cell proliferation & migration and MSP-independent increased cell survival.breast,
The expression of several oncogenic RON splice variants in malignant gliomas suggests that these could represent candidate targets for treatment with agents inhibiting RON activityglioma,
Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors. pancreatic,gastric,
Data suggest that oncogenic RON160 is frequently expressed in primary invasive ductal, lobular, and lymph node-involved breast cancer tissues; RON160 overexpression is predominantly observed in invasive ductal and lymph node-involved cases.breast,
the activated beta-catenin cascade is one of the pathways involved in tumorigenic activities mediated by the oncogenic RON variantNone
Pro-metastatic splicing of Ron proto-oncogene mRNA can be reversed: therapeutic potential of bifunctional oligonucleotides and indole derivatives. None
macrophage stimulating 1 receptor is associated with invasive and oncogenic phenotypes such as tumor cell migration, invasion, resistance to apoptosis and cell cycle arrestNone
Identification of novel splicing variants from RON proto-oncogene pre-mRNA. None
Knockdown of RON inhibited invasive growth & the activation of oncogenic signaling pathways including Akt, MAPK and beta-catenin. RON up-regulation was associated with tumor size, lymphatic metastasis, invasiveness, tumor stage and poor survival.None
A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene. None
Hypoxia promotes nuclear translocation and transcriptional function in the oncogenic tyrosine kinase RON. None
SRSF2 promotes exon 11 inclusion of Ron proto-oncogene through targeting exon 11.None
Aberrant glycosylation of the RON receptor was shown as an alternative mechanism of oncogenic activation.None
the cis-regulatory landscape that determines alternative splicing of exon 11 in the proto-oncogene MST1R (RON), was examined.None