| MUC1-C oncoprotein activates ERK-->C/EBPbeta signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cells. | breast, |
| MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells. | leukemia, |
| Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells. | breast, |
| MUC1 is known as an oncogene with an anti-apoptotic function in cancer cells; in normal gastric mucosa, MUC1 has a role in protecting gastric epithelial cells from a variety of external insults which cause inflammation and carcinogenesis. | gastric, |
| Mucin 1 gene (MUC1) and gastric-cancer susceptibility. | gastric, |
| Targeting the oncogenic MUC1-C protein inhibits mutant EGFR-mediated signaling and survival in non-small cell lung cancer cells. | lung, |
| MUC1 oncogenic mucin alters proliferation, migration, and invasion properties of pancreatic cancer cells and that these effects are mediated by p42-44 MAPK, Akt, Bcl-2 and MMP13 pathways. | pancreatic, |
| identified miR-29a and miR-330-5p as two new tumor suppressive miRNAs that inhibit the expression of MUC1 oncogenic mucin in pancreatic cancer cells. | pancreatic, |
| Up-regulation of MUC1 in mammary tumors generated in a double-transgenic mouse expressing human MUC1 cDNA, under the control of 1.4-kb 5 MUC1 promoter sequence and the middle T oncogene, expressed from the MMTV promoter. | None |
| Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein. | None |
| Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. | None |
| The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. | None |
| MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. | None |
| Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. | None |
| MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90. | None |
| MUC1 oncoprotein stabilizes and activates estrogen receptor alpha. | None |
| MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage. | None |
| Mucin 1 oncoprotein blocks hypoxia-inducible factor 1alpha activation in a survival response to hypoxia. | None |
| MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling. | None |
| Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene. | None |