| OGG1 and MYH function as suppressors for G:C to T:A transversions by 8OHG but not by BPDE in human cells. | unknown |
| ability of MUTYH and the variants to suppress mutations and complement for the absence of MutY in Escherichia coli was assessed using rifampicin resistance assays. | unknown |
| These results suggested that MUTYH is a suppressor of mutations caused by 8OHG in gastric cells and that its reduced expression is associated with a poor prognosis in gastric cancer. | gastric |
| p.R154H, p.M255V, p.L360P, and p.P377L MUTYH variants have suppressive activities against mutations caused by 8OHG are thought to be severely impaired in human cells | unknown |