Sentence and cancer type
Showing 581-600 of 1,084 items.
SentenceCancertype
25 years of the c-Myc oncogene. None
The c-myc proto-oncogene regulates cardiac development in transgenic mice. None
Clonally related IL-7-independent tumors induced by oncogenes abl + myc or raf + myc have reduced sensitivity to TGF-beta1.None
complete regression of tumor mass driven by inactivation of the MYC oncogene requires the p53-dependent induction of thrombospondin-1 and the shut down of angiogenesisNone
Antiproliferative effects of antisense oligonucleotides directed to the RNA of c-myc oncogene. None
Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc. None
DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice. None
identify c-MYC as an essential mediator of NOTCH1 signaling and integrate NOTCH1 activation with oncogenic signaling pathways upstream of c-MYCNone
The c-Myc oncogene expression was very low in normal and cancer tissues but highly increased in papillomatosis.None
[Amplification of L-myc oncogene in malignant meningioma. Case report]. None
Histological detection of c-myb and c-myc proto-oncogene expression in infiltrating cells in cutaneous lupus erythematosus-like lesions of MRL/l mice by in situ hybridization. None
oncogenic deregulation of c-MYC prevents repair of replication-stress induced DNA lesions in G(2)-phase; suggests c-MYC-mediated persistence of DNA lesions during mitosis leads to chromosomal missegregation & underlies c-MYC-induced chromosome instabilityNone
Induction of apoptosis and autophagic cell death by the vanillin derivative 6-bromine-5-hydroxy-4-methoxybenzaldehyde is accompanied by the cleavage of DNA-PKcs and rapid destruction of c-Myc oncoprotein in HepG2 cells. None
Expression of exogenous c-myc oncogene does not initiate DNA synthesis in primary rat hepatocyte cultures. None
Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives. None
Investigation of nuclear c-MYC oncoprotein expression in human hematopoiesis: suitability of a rapid and reliable semiquantitative evaluation system. None
Metabolic enzymes regulated by the Myc oncogene are possible targets for chemotherapy or chemoprevention. None
Mnt takes control as key regulator of the myc/max/mxd network. None
Myc is the most frequently deregulated oncogene in human tumors. Myc function relies on overcoming transcriptional repression by Mnt. Relief of Mnt-mediated repression is more important for target gene regulation than the sole activation by Myc. Review.None
observations raise the possibility that unscheduled replication origin activation at inserted HPV-18 viral DNA sequences triggers DNA amplification in this cancer cell line and the subsequent overexpression of the MYC oncogeneNone