Sentence and cancer type
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SentenceCancertype
Prostate cancer linkage to the same region of 16q23 has been observed by others and the region contains several strong candidate genes including the known prostate cancer tumor suppressor genes ATBF1 and WWOX.prostate,
These findings provide in vivo evidence that ATBF1 is a tumor suppressor in the prostateprostate,
ATBF1 associates with RUNX3 and translocates to the nucleus in response to TGF-beta signal transduction and might function in the nucleus as tumor suppressor and transcriptional regulator.None