| Suggest critical role for tumor suppressor ATF3 in esophageal squamous cell carcinoma progression. | esophageal, |
| results thus link ATF3 to the AKT signaling, and suggest that ATF3 is a tumor suppressor for the major subset of prostate cancers harboring dysfunctional Pten | prostate, |
| Study identified ATF3 as a tumor suppressor for inhibiting cell proliferation and metastasis in hepatocellular carcinoma (HCC) through targeting and regulating CYR61. Clinically, ATF3 was down-regulated in HCC tissues, and its expression significantly associated with intrahepatic metastases and overall survival. | liver, |
| ATF3 can suppress mutp53 oncogenic function, thereby contributing to tumor suppression in TP53-mutated cancer | None |
| ATF3 and EGR1 are involved in the beginning of inflammatory processes. Whether these two transcription factors act as tumour suppressors or promoters is context dependent and warrants analysis in further studies | None |
| ATF3 may play an oncogenic role in human breast tumorigenesis, and therefore may be useful as either a biomarker or therapeutic target. | breast, |
| ATF3 may have oncogenic properties in epithelial cells | None |
| The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis. | None |
| activating transcription factor 3 appears to play an oncogenic role in the development of squamous cell carcinomas and may be related to the biologic behavior of them. | None |
| The oncogene ATF3 is potentiated by cyclosporine A and ultraviolet light A. | None |