| results show that rare, protein-coding germline variants in ATM are frequent events in chronic lymphocytic leukemia, with ATM behaving as a classic tumor suppressor gene, showing preferential somatic loss of the wild-type allele | leukemia, |
| results indicate that KSHV vIRF1 comprehensively compromises an ATM/p53-mediated DNA damage response checkpoint by targeting both upstream ATM kinase and downstream p53 tumor suppressor | None |
| analysis of the three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with | None |
| ATM-dependent response to DNA damage caused by deregulated expression of E2F3a is important for the induction of apoptosis and tumor suppression | None |
| p53 retains tumor suppressor activity in the absence of Atm. | None |
| The tumor suppressor function of HINT1 is caused by, at least in part, its normal role in enhancing cellular responses to DNA damage by regulating the functions of both gamma-H2AX and ATM. | None |
| these results elucidate a novel mechanism through which the TGF-beta pathway regulates the cancer stem cells property by interfering with the tumor suppressor ATM. | None |
| Genomic profiling and exome sequencing identify ATM as a tumor suppressor gene and confirm that germline ATM mutations are involved in a subset of familial BC. | None |