Sentence and cancer type
Showing 21-40 of 42 items.
SentenceCancertype
NF1 tumor suppressor mRNA is targeted to the cell-cell contact zone in Ca(2+)-induced keratinocyte differentiation.None
NF1 tumor suppressor may function in the regulation of epidermal histogenesis via controlling the organization of the keratin cytoskeleton during the assembly of desmosomes and hemidesmosomes.None
Increased noise as an effect of haploinsufficiency of the tumor-suppressor gene neurofibromatosis type 1 in vitro.None
Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor.None
Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.None
Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.None
Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells.None
NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos.None
The effect of extracellular calcium concentration on calcium-mediated cell signaling in NF1 tumor suppressor-deficient keratinocytes.None
NF1 tumor suppressor critically regulates TSC2 and the mTOR pathway.None
A conditional allele of the NF1 tumor suppressor that negatively regulates Ras signaling together with inactivation of p53 induce malignant astrocytoma.None
The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways.None
Nf1 expression is dependent on strain background: implications for tumor suppressor haploinsufficiency studies.None
Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2.None
A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.None
In addition to gains of 1q and 5p, and losses of 10p and 13q14 approximately q22, this tumor had also losses of two regions to which tumor suppressor genes are mapped: 1p36 (SDHB) and 17q11.2 (NF1)None
The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo.None
Findings define a tumor suppressor role for Nf1 in the adult and narrow the range of potential neurofibroma-initiating cell populations.None
Authors used a pooled RNA interference screen targeting more than 16,500 genes to discover loss-of-function events that could drive resistance to RAF inhibition. The highest ranking gene was NF1 a tumor suppressor that inhibits RAS activity.None
Study reveals the NF1 tumor suppressor gene as a new mediator of resistance to EGFR tyrosine kinase inhibitors.None