| NPM has a tumor suppressive role in breast cancer | breast, |
| Npm1 acts as a haploinsufficient tumor suppressor in the hematopoietic compartment | None |
| HLJ1 switches the role of NPM1, which can act as tumor suppressor or oncogene, by modulating the oligomerization of NPM1 via HLJ1-NPM1 heterodimer formation and recruiting AP-2alpha to the MMP-2 promoter. | None |
| Targeting the oncogenic tyrosine kinase NPM-ALK in lymphoma: the role of murine models in defining pathogenesis and treatment options. | lymphoma, |
| The leukemia-associated NPMc+ is an in vitro oncogene under the appropriate genetic context | leukemia, |
| The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence. | leukemia, |
| Oncogenic NPM1-ALK contains the NPM1 oligomerization motif plus ALK catalytic domain and mediates malignant cell transformation by epigenetic silencing of signal transducer and activator of transcription STAT5A in T-cell anaplastic large cell lymphomas. | lymphoma, |
| IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells. | lymphoma, |
| NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells. | lymphoma, |
| Data suggest that Akt2/B23 functions as an oncogenic unit to drive tumorigenesis of A549 lung cancer cells. | lung, |
| The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway. | lymphoma, |
| The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein. | lymphoma, |
| Expression of the oncogenic NPM-ALK chimeric protein in human lymphoid T-cells inhibits drug-induced, but not Fas-induced apoptosis. | None |
| A liaison dangereuse between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK. | None |
| Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation. | None |
| A novel mechanism of nucleophosmin (NPM) tumorigenesis establishes NPM as a crucial inhibitor of oncogene-induced apoptosis and senescence. | None |
| Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).( | None |
| Serine phosphorylation of NPM-ALK, contributes to its oncogenic potential. | None |
| Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS. | None |
| The pathobiology of the oncogenic tyrosine kinase NPM-ALK: a brief update. | None |