| Results identify a crucial tumor suppressive role of miR-424 in the progression of cervical cancer at least partly via upreglating the expression of Chk1. | cervical, |
| Findings indicate that miR-424 targets the E2F7 transcript and suppresses endometrial cancer cell growth, suggesting that miR-424 has a tumor suppressive role in human endometrial cancer pathogenesis. | endometrial, |
| research suggests that miR424-5p may act as a novel anti-oncogene in cervical cancer by blocking cell growth through targeting KDM5B-Notch pathway | cervical, |
| miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy | breast, |
| The data of this study suggest that the promoter region CpG island methylation is associated with tumor suppressive miR-424 silencing and the pathology of human gliomas. | glioma, |
| miR-424-5p is a tumor suppressive microRNA to regulate tumor cell proliferation, migration and invasion via binding to the functional target DCLK1, and associated with malignant status in basal-like breast cancer | breast, |
| Study showed that miR424 expression was decreased in the majority of human breast cancer and cell lines, and demonstrated that miR424 acted as a tumor suppressor in breast cancer cells. Its overexpression suppressed cell growth and disrupted the cell cycle, likely by targeting CDK1. | breast, |
| miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer | colorectal, |
| Tumor suppressive activity of miR-424-5p in breast cancer cells through targeting PD-L1 and modulating PTEN/PI3K/AKT/mTOR signaling pathway | breast, |
| Tumor suppressor miR-424-5p abrogates ferroptosis in ovarian cancer through targeting ACSL4 | ovarian, |