| The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver. | liver, |
| Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. | ovarian, |
| GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia. | leukemia, |
| Autophagy collaborates with ubiquitination to downregulate oncoprotein E2A/Pbx1 in B-cell acute lymphoblastic leukemia. | leukemia, |
| PBX1 plays an oncogenic role in clear cell renal carcinoma via JAK2/STAT3 pathway | kidney, |
| EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1. | None |
| mAngiogenin-3, a target gene of oncoprotein E2a-Pbx1, encodes a new angiogenic member of the angiogenin family. | None |
| Transcriptional profiling during the early differentiation of granulocyte and monocyte progenitors controlled by conditional versions of the E2a-Pbx1 oncoprotein. | None |
| E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells. | None |
| PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1. | None |
| B-cell development fails in the absence of the Pbx1 proto-oncogene. | None |
| Oligomeric self-association contributes to E2A-PBX1-mediated oncogenesis. | None |
| Oncoprotein E2A-Pbx1 immortalizes a myeloid progenitor in primary marrow cultures without abrogating its factor-dependence. | None |
| Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable. | None |
| Dpbx, a new homeobox gene closely related to the human proto-oncogene pbx1 molecular structure and developmental expression. | None |
| extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1. | None |
| DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation. | None |
| The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis. | None |
| Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo. | None |
| A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. | None |