| Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma. | esophageal, |
| The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis. | pancreatic, |
| Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas. | oral |
| Activated tyrosine kinase Ack1 promotes prostate tumorigenesis by tyrosine phosphorylation of tumor suppressor Wwox at Tyr-287. It leads to polyubiquitination and degradation. | prostate, |
| WWOX overexpression in prostate cancer cells suppressed colony growth and induced apoptosis. Data are consistent with a role for WWOX as a prostate cancer tumor suppressor. | colorectal,prostate, |
| Wwox hypomorphs had an increased incidence of B-cell lymphomas supports a role of Wwox as a tumor suppressor | lymphoma, |
| Molecular alterations in the tumor suppressor gene WWOX in oral leukoplakias. | oral |
| Decreased expression of the WWOX tumour suppressor genemay be of importance for the development of human intracranial meningiomas | meningiomas, |
| The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX. | liver, |
| Prostate cancer linkage to the same region of 16q23 has been observed by others and the region contains several strong candidate genes including the known prostate cancer tumor suppressor genes ATBF1 and WWOX. | prostate, |
| Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells. | prostate, |
| WWOX acts as an ovarian tumor suppressor by modulating the interaction between tumor cells and the extracellular matrix, decreasing integrin activity and adhesion of tumor cells to fibronectin. | ovarian, |
| Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression. | osteosarcoma, |
| Bmi1 regulates cell fate via tumor suppressor WWOX repression in small-cell lung cancer cells. | lung, |
| the WWOX tumor suppressor gene has in preventing tumorigenesis in breast cancer | breast, |
| Evidences that the polymorphism Pro-282-Ala within the tumor suppressor gene WWOX is a new risk factor for differentiated thyroid carcinoma. | thyroid, |
| Using the Affymetrix 6.0 SNP array, the study shows that tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma cell lines. | lymphoma, |
| Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines. | lymphoma, |
| our study confirmed again the tumor suppressor role of WWOX in human renal cell carcinoma. | kidney, |
| Modeling WWOX inactivation revealed a complex phenotype including postnatal lethality, defects in bone metabolism and steroidogenesis and tumor suppressor function resulting in osteosarcomas. | osteosarcoma, |