| WWOX is a member of a very interesting family of very large common fragile site genes and functions as a tumor suppressor involved in the development of many cancers. | None |
| miR-153 inhibited protein level of WWOX, a tumor suppressor and inhibitor of beta-catenin signaling, through targeting its 3_-untranslated region. | None |
| In Memoriam: Shur-Tzu (Su) Chen, a pioneer in tumor suppressor WWOX for neuroscience | None |
| Together these results provide a molecular basis for the tumor suppressor functions of WWOX and the better prognosis observed in cancer patients with higher levels of WWOX activity. | None |
| the ability of WWOX to facilitate escape from mitochondrial damage-induced glycolysis (Warburg effect) is, therefore, a plausible mechanism for its tumor suppressor activity. | None |
| Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells | None |
| PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome | None |
| Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events | None |
| WWOX functions as a mammary tumor suppressor, likely through mediating genome stability in a p53-dependent mechanism, and its loss of function in mammary epithelium reproduces several important features of BLBCs. | None |
| Cancerous Protein Network That Inhibits the Tumor Suppressor Function of WW Domain-Containing Oxidoreductase (WWOX) by Aberrantly Expressed Molecules | None |
| The studies uncover an unforeseen role of the tumor suppressor WWOX in whole-body glucose homeostasis and highlight the intimate relationship between cancer progression and metabolic disorders, particularly obesity and type-2 diabetes. | None |
| The tumor suppressor gene WWOX is a novel target of miR-187* in SiHa cells. WWOX siRNA suppressed endogenous WWOX expression and increased the oncogenic phenotypes of SiHa cells. Exogenous WWOX expression was able to suppress the oncogenic phenotypes of SiHa cells and rescue cells from miR-187*-induced migration. | None |
| Pleiotropic tumor suppressor functions of WWOX antagonize metastasis | None |
| Virus-encoded miR-155 ortholog in Marek_s disease virus promotes cell proliferation via suppressing apoptosis by targeting tumor suppressor WWOX | None |
| The tumor suppressor gene WWOX is a novel target of miR-187* in SiHa cells. WWOX siRNA suppressed endogenous WWOX expression and increased the oncogenic phenotypes of SiHa cells. Exogenous WWOX expression was able to suppress the oncogenic phenotypes of SiHa cells and rescue cells from miR-187*-induced migration. | None |