| The study suggest that the tumor suppressing action of prohibitin is probably associated with luteinizing hormone mediated protection role against ovarian epithelial carcinoma. | ovarian, |
| Study gives attention to the functional role and regulatory mechanism of PHB proteins in cardiovascular health and diseases (VCD) and its associated implications. Various molecular pathways involved in PHB function and its regulation are analyzed. In neoplasm, PHB is shown to act through many mechanisms by acting as oncogene, tumor suppressor, antioxidant, antiapoptotic, in angiogenesis, autophagy etc. [review] | neoplasm, |
| Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function. | None |
| PHB is reported to have tumour suppressor, anti-proliferative and cell cycle regulation activities, largely accomplished through its repression of E2F activity. | None |
| These results suggest that the altered localization and expression of PHB, as well as its co-localization with related oncogenes and tumor suppressor genes, can affect the apoptosis of Mz-ChA-1 cells. | None |