Sentence and cancer type
Showing 21-40 of 53 items.
SentenceCancertype
Interactions between RPS19, mutated in Diamond-Blackfan anemia, and the PIM-1 oncoprotein. None
The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C. None
Mapping of the Pim-1 oncogene in mouse t-haplotypes and its use to define the relative map positions of the tcl loci t0(t6) and tw12 and the marker tf (tufted). None
PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation. None
The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes. None
The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG. None
Stability changes in pim-1 proto-oncogene mRNA after mitogen stimulation of normal lymphocytes. None
The oncogenic PIM kinase family regulates drug resistance through multiple mechanisms. None
RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes. None
An RNA G-quadruplex in the 3 UTR of the proto-oncogene PIM1 represses translation. None
study identified a conserved G-quadruplex forming sequence in the 3_ untranslated region (UTR) of the proto-oncogene PIM1; reporter gene assay demonstrated that the PIM1 RNA G-quadruplex represses translationNone
The proto-oncogene Pim-1 is a target of miR-33a. None
Primary structure of the putative human oncogene, pim-1. None
Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1. None
Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells. None
Fragment-hopping-based discovery of a novel chemical series of proto-oncogene PIM-1 kinase inhibitors. None
Inhibition of the Pim1 oncogene results in diminished visual function. None
This study demonstrates the oncogenic role of Pim-1 in ACC. The findings also suggest that Pim-1 may serve as a neoteric therapeutic target and potential prognostic marker for ACC cancerNone
Pim kinase may represent a new host factor for HCV entry. Pim1 is an oncogenic serine/threonine kinase. HCV NS5A protein physically interacts with Pim1 and contributes to Pim1 protein stability.None
Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene Kinase Pim-1. None