| Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers. | HNSC, |
| ING3 would function as a potential tumor suppressor molecule and that low levels of ING3 may indicate an aggressive nature of head and neck cancer. | HNSC, |
| ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. | None |
| The tumor suppressor ING3 is degraded by SCF(Skp2)-mediated ubiquitin-proteasome system. | None |
| results reveal the molecular mechanism of H3K4me3 selection by the ING3PHD and suggest that this interaction is important for mediating ING3 tumor suppressive activities. | None |