| Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma. | liver, |
| Data show that liver-related putative tumor suppressor gene (LPTS) mutations occur in hepatocellular carcinoma but are infrequent and of little effect on the telomerase inhibitory function of the protein. | liver, |
| These results confirmed the role of PinX1 as a major tumor suppressor gene in breast cancer cell lines. | breast, |
| Data show a novel molecular mechanism for PINX1 as an attenuator of estrogen receptor activity in breast cancer cell lines, furthering its role as a tumor suppressor gene in breast cancer. | breast, |
| Our findings suggested that PinX1 could be a potential tumour suppressor in non-small-cell lung cancer and that loss of PinX1 promoted non-small-cell lung cancer progression. | lung, |
| The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice. | None |