| Tumor-suppressor Fbxw7 targets SIK2 for degradation to interfere with TORC2-AKT signaling in pancreatic cancer | pancreatic, |
| FBXW7? is a tumor-suppressive and prognosis-related FBXW7 transcript isoform in ovarian serous cystadenocarcinoma | ovarian, |
| MicroRNA?92a promotes non?small cell lung cancer cell growth by targeting tumor suppressor gene FBXW7 | lung, |
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. | None |
| FBXW7/hCDC4 is a general tumor suppressor in human cancer. | None |
| The Fbxw7/hCdc4 tumor suppressor in human cancer. | None |
| The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs. | None |
| Tumor suppressor Fbxw7 regulates TGF?? signaling by targeting TGIF1 for degradation. | None |
| F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor. | None |
| C/EBPdelta directly inhibits expression of the tumour suppressor F-box and WD repeat-domain containing 7 gene (FBXW7, FBW7, AGO, Cdc4), encoding an F-box protein that promotes degradation of the mammalian target of rapamycin (mTOR). | None |
| The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis. | None |
| Fbw7, a tumor suppressor and ubiquitin ligase, binds to CDK8-Mediator and targets MED13/13L for degradation | None |
| Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. | None |
| The tumor suppressor FBW7 controls ciliary length | None |
| Fbxw7 Tumor Suppressor: A Vital Regulator Contributes to Human Tumorigenesis | None |
| Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7? | None |
| identify a tumor suppressor mechanism in the mammalian intestine that arises from the posttranslational regulation of FBW7 by USP9X independent of somatic FBW7 mutations. | None |
| FBXW7 is an essential tumor suppressor and is frequently inactivated in human cancer cells. In addition to genetic mutations, other mechanisms involving microRNA, long non-coding RNA, and specific oncogenic signaling pathways can inactivate FBXW7 functions in cancer cells. [review] | None |
| The Tumor Suppressor FBW7 and the Vitamin D Receptor Are Mutual Cofactors in Protein Turnover and Transcriptional Regulation | None |
| Recent insight into the role of FBXW7 as a tumor suppressor | None |