Sentence and cancer type
Showing 1-9 of 9 items.
SentenceCancertype
Regulatory subunit type I-alpha of protein kinase A (PRKAR1A): a tumor-suppressor gene for sporadic thyroid cancer.thyroid,
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice.osteosarcoma,
PRKAR1A could function as a tumor suppressor gene in pancreatic tissue, at least in the context of Carney complex.pancreatic,
Prkar1a is indeed a tumor suppressor in the thyroid and that loss of this gene leads to hyperthyroidism and follicular thyroid cancerthyroid,
PRKAR1A is a potent tumor suppressor that inhibits the ERK/Snail/E-cadherin pathway in lung adenocarcinomalung,
PRKAR1A might function as a tumor suppressor geneNone
the tTA/X2AS mouse line with a downregulated Prkar1a gene replicates several of the findings in Carney complex patients and their affected tissues, supporting the role of RI as a candidate tumour suppressor geneNone
Reviews genetic aspects of hereditary GH-secreting tumors and data from animal models resulting from the inactivation of the PRKAR1A tumor suppressor gene.None
This mouse knockout model supports the role of prkar1a as a tumor suppressor gene in the pancreas and points to the PKA pathway as a possible therapeutic target for these lesions.None