| CHFR might act as a tumor suppressor in at least some colorectal cancers and that CHFR methylation might, therefore, be a particular phenomenon of early colorectal cancer | colorectal, |
| CHFR has a role as a tumor suppressor in breast cancer | breast, |
| Chfr activation by USP7 may play an important role in the regulation of Chfr-mediated cellular processes including cell cycle progression and tumor suppression. | None |
| confirmed that the FHA domain of CHFR plays an important role in initiating a cell cycle arrest at G2/M, indicating a functional link exists between the anti-proliferative effects and checkpoint function of this tumor suppressor protein via this domain | None |
| Chfr functions as a tumour suppressor by regulating HDAC1. | None |
| CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-kappaB. | None |