Showing 1-2 of 2 items.

Sentence	Cancertype
the proto-oncogenic property of the MEK/ERK pathway in hematopoietic cells can manifest in MDS/MPN development	None
This is the first report of MAP2K1 mutations in Langerhans cell histiocytosis(LCH) that occur in 50% of BRAF wild-type cases. The mutually exclusive nature of MAP2K1 and BRAF mutations implicates a critical role of oncogenic MAPK signaling in LCH.	None