| PROX1 functions as a tumor suppressor gene in oral carcinogenesis. | oral |
| PROX1 gene corresponds to that of a candidate tumor-suppressor gene. | None |
| mechanisms like genomic deletions and hypermethylation, which are prototypic for the inactivation of tumor suppressor genes, inactivate PROX1 in carcinomas of the bilary system | None |
| PROX1 serves an oncogenic role in glioblastoma multiforme and promotes cell proliferation and invasiveness potentially via activation of the NFkappa B signaling pathway. | glioblastoma, |