Sentence and cancer type
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Sentence
Cancertype
Identification of functionally distinct TRAF proinflammatory and phosphatidylinositol 3-kinase/mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (PI3K/MEK) transforming activities emanating from RET/PTC fusion oncoprotein.
None
during Hedgehog signaling, ligand binding inhibits Patched by trapping it in an inactive conformation, a mechanism that explains the dramatically reduced activity of oncogenic Patched1 mutants.
None
Activated RET/PTC oncogene elicits immediate early and delayed response genes in PC12 cells.
None
Development of mammary and cutaneous gland tumors in transgenic mice carrying the RET/PTC1 oncogene.
None
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