Sentence and cancer type
Showing 101-120 of 231 items.
SentenceCancertype
Promoter analysis of tumor suppressor gene PTEN: identification of minimum promoter region.None
Reversible inactivation of the tumor suppressor PTEN by H2O2.None
Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.None
Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation.None
Knockout mice lacking Pten show abnormalities in tumor suppression, immune function and embryo development.None
The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells.None
Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3: implications for the control of protein stability and PTEN-protein interactions.None
tumor suppressor PTEN, inhibits the interaction of CH-ILKBP with ILKNone
Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop.None
Perlecan-induced suppression of smooth muscle cell proliferation is mediated through increased activity of the tumor suppressor PTEN.None
Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphatase.None
results show that PTEN can inhibit cell migration through its C2 domain, independent of its lipid phosphatase activity; ability of PTEN to control cell migration through its C2 domain is likely to be an important feature of its tumor suppressor activityNone
the tumor suppressor PTEN has a profound effect on differentiation by affecting several pathways involved in nerve growth factor signalingNone
a tumour suppressor candidate protein binds to extreme C-terminal region of PTEN and regulates PTEN protein turnover [review]None
One common way of stimulating the 1-Phosphatidylinositol 3-Kinase kinase pathway occurs through inactivation of the PTEN tumor suppressorNone
We found that indomethacin and NS-398 treatment significantly upregulated expression of the tumor suppressor gene, PTEN.None
increased levels of Trx-1 in human tumors could lead to functional inhibition of PTEN tumor suppressor activity providing an additional mechanism for tumorigenesis with loss of PTEN activityNone
Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein.None
Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.None
Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics.None