| Nuclear PTEN is essential for tumor suppression and that PTEN nuclear import is mediated by its monoubiquitination. | None |
| Presenilins regulate the cellular level of the tumor suppressor PTEN. | None |
| Role of tumor suppressor PTEN in tumor necrosis factor alpha-induced inhibition of insulin signaling in murine skeletal muscle C2C12 cells. | None |
| bi-allelic inactivation of PTEN can lead to developmental anomalies instead of malignant transformation, thus raising the question of the limitations of the tumor suppressive function in this gene. | None |
| Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. | None |
| In patients with mycosis fungoides, several loci associated with the tumor suppressor gene PTEN on chromosome 10 appear to be associated with progression from plaque to tumor stage. | None |
| Cell cycle progression from the G(1) to the S phase is arrested in cells expressing wild-type PTEN, suggesting a role for PTEN as a tumor suppressor gene. | None |
| (PTEN) tumor suppressor gene as a target of MAD1. | None |
| Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade. | None |
| The mitochondrial localization of tumor suppressor PTEN promotes apoptosis in A431 cells. | None |
| Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. | None |
| VHL mutation alone is insufficient for tumor formation; study shows that epididymal cystadenomas from VHL patients frequently also lack expression of the PTEN tumor suppressor and display activation of phosphatidylinositol 3-kinase pathway signaling. | None |
| A cross-talk between oncogenic Ras and tumor suppressor PTEN through FAK Tyr861 phosphorylation in NIH/3T3 mouse embryonic fibroblasts. | None |
| Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes. | None |
| The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision. | None |
| A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. | None |
| Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications. | None |
| The integration of PTEN and p53 into a common pathway for the induction of another tumor suppressor, Maspin, constitutes a tumor suppressor network of PTEN/p53/Mapsin that is operational under limited oxygen conditions. | None |
| Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia. | None |
| Myeloid-specific deletion of tumor suppressor PTEN augments neutrophil transendothelial migration during inflammation. | None |