| MiRNA-451 plays a role as tumor suppressor in human glioma cells. | glioma, |
| MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). | lung, |
| miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in primary gastric cancer. | gastric, |
| MiR-451, a potential prognostic biomarker and tumor suppressor for gastric cancer | gastric, |
| MicoRNA-451 is a novel tumor suppressor via targeting c-myc in head and neck squamous cell carcinomas | HNSC, |
| MiR-451 acts as an anti-oncogene in renal cell carcinoma. | kidney, |
| our study provide both an updated overview of miRNA deregulation in Papillary Thyroid Carcinoma and the first functional evidence that miR-451a exerts tumor suppressor functions in this neoplasia. | thyroid, |
| This discovery suggested that miR-451 is a tumor suppressor modulating bladder cancer cell migration and invasion by directly targeting c-Myc | bladder, |
| these findings provided that in lung cancer cells, tumor suppressor miR-451 enhanced DPP sensitivity via regulation of Mcl-1 expression, which could be served as a novel therapeutic target for the treatment of chemotherapy resistant in lung cancer. | lung, |
| Exosomal miR-451a Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Targeting LPIN1 | liver, |
| This study, we performed a comprehensive analysis of putative human miRNA oncogenes and tumor suppressors. We found that miRNA oncogenes and tumor suppressors clearly show different patterns in function, evolutionary rate, expression, chromosome distribution, molecule size, free energy, transcription factors, and targets. | None |
| Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL. | None |
| data indicate that miR-145 and miR-451 act as tumor suppressors in adipose tissue | None |
| miR-451 behaves as a tumor suppressor, probably by targeting the IL6R pathway | None |
| these results reveal a prominent role of miR-451 as a tumor suppressor regulating hepatoma cell growth and invasion | None |
| Loss of tumour suppressive miR-451a enhanced cancer cell migration and invasion in HSCC through direct regulation of ESDN. | None |
| Using pharmacological and in vivo techniques, the study provide evidence that MIR-451 functions as a tumor suppressor gene through modulation of CARF expression. | None |
| MicroRNA-451a acts as tumor suppressor in cutaneous basal cell carcinoma | None |