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overexpressed in hepatocellular carcinoma and aids in transformation by regulating the G1/S cell cycle transition through targeting of the Mutated in Colorectal Cancer tumor suppressor
colorectal,liver,
miR-494 repressed the expression of HOXA10 and also reduced the proliferation of oral cancer cells. These data give more evidence of the role of miR-494 as a tumor suppressor miRNA in oral cancer.
oral
MicroRNA-494 acts as a tumor suppressor in pancreatic cancer, inhibiting epithelial-mesenchymal transition, migration and invasion by binding to SDC1
pancreatic,
miR494 expression was significantly lower in synovial sarcoma (SS) tumors concomitantly with an increased expression of its potential target, CXCR4, and even more evident in the metastatic subset. In vitro experiments confirmed that miR494.3p functioned as a tumor suppressor through the involvement of CXCR4.
sarcoma,
miR-494 and GALNT7 play oncogenic roles in nasopharyngeal carcinoma.
nasopharyngeal,laryngeal,