| miR-497 is a candidate tumor suppressor in neuroblastoma, through the direct targeting of WEE1. | neuroblastoma, |
| Tumor-suppressive microRNA-497 targets IKK? to regulate NF-?B signaling pathway in human prostate cancer cells | prostate, |
| we demonstrated that miR-497 is decreased in human ovarian cancer tissues and cells, and acts as a tumor suppressor. We also confirmed PAX2 is a target gene of miR-497 | ovarian, |
| Tumor suppressor miR-497-5p down-regulates KCa3.1 expression and contributes to the inhibition of angiosarcoma malignancy development. | sarcoma, |
| miR-497 could serve as a tumor suppressor and a potential early diagnostic marker of gastric cancer by targeting Raf-1 proto-oncogene. | gastric, |
| These findings indicate miR-497 as a tumor suppressor results from negative regulation of the MAPK/ERK signaling pathway via RAF-1 in cervical cancer. | cervical, |
| Knockdown of Wnt3a mimicked the effect of miR-497 in glioma cells. In summary, our study demonstrated that miR-497 may function as a tumor suppressor in glioma and suggested that miR-497 is a potential therapeutic target for glioma patients | glioma, |
| miR-497, functioning as a tumor suppressor gene, inhibits the growth of laryngeal squamous cell carcinoma by targeting CDK6. | laryngeal, |
| Study demonstrated that miR497 was downregulated in nonsmall cell lung cancer (NSCLC) specimens and it served as a tumor suppressor to inhibit cancer cell proliferation and invasion, and increase radiosensitivity via targeting KDR. | lung, |
| The results of the present study identified miR497 as a potential tumor suppressor gene in nonsmall cell lung cancer that may function via repressing FGFR1 expression, and AKT and JNK signaling. | lung, |
| hese findings demonstrate that miR-195 and miR-497 act as a tumor suppressor by suppressing ubiquitination-mediated degradation of TGF-beta receptors through SMURF2, and suggest that miR-195 and miR-497 are potential therapeutic targets for lung cancer. | lung, |
| Findings indicate that miR-497 is a potent tumor suppressor that inhibits cancer phenotypes by targeting ANLN and HSPA4L in NPC. | None |