| NDRG2 might play an important role in the carcinogenesis and development of clear cell renal cell carcinoma and may function as a tumor suppressor in clear cell renal cell carcinoma | kidney, |
| [Expression of candidate tumor suppressor gene N-Myc downstream-regulated gene 2 in colon cancer]. | colorectal, |
| NDRG2 as a candidate tumor suppressor gene that is epigenetically silenced in the majority of primary glioblastomas, but not in lower grade astrocytomas and secondary glioblastomas. | glioblastoma,astrocytomas, |
| [Expression and significance of new candidate tumor suppressor gene N-Myc downstream-regulated gene 2 in colorectal cancer]. | colorectal, |
| NDRG2 is a candidate tumor-suppressor for oral squamous-cell carcinoma. | oral |
| Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression | colorectal, |
| These findings indicate that SUMOylation of NDRG2 is necessary for its tumor suppressor function in lung adenocarcinoma and that RNF4 increases the efficiency of this process. | lung, |
| putative tumor suppressive function of NDRG2 may be confined to luminal- and basal B-type breast cancers | breast, |
| The tumor suppressor NDRG2 cooperates with an mTORC1 inhibitor to suppress the Warburg effect in renal cell carcinoma | kidney, |
| Data identify NDRG2 as the first specific candidate tumor suppressor gene on chromosome 14q that is inactivated during meningioma progression. | None |
| Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor. | None |
| Authors investigate the clinical and pathological role of NDRG2 in human malignant tumors. The absence of NDRG2 expression is associated with oncogenic properties through the loss of its role as a tumor suppressor; NDRG2 overexpression inhibits proliferation, adhesion, and invasion, whereas its expression is low or undetectable in various cancers. [Review] | None |
| Deficiency of tumor suppressor NDRG2 leads to attention deficit and hyperactive behavior | None |
| The microRNA miR-375-3p and the Tumor Suppressor NDRG2 are Involved in Sporadic Amyotrophic Lateral Sclerosis | None |