| data demonstrate that PTK7 binds and activates FGFR1 independent of FGF and thus increases oncogenicity of PTK7- and FGFR1-positive cancers such as esophageal squamous cell carcinoma. | esophageal, |
| The GxxxG-containing transmembrane domain of the CCK4 oncogene does not encode preferential self-interactions. | None |
| Furthermore, we confirmed that these phenotypic changes are associated with the inactivation of AKT and ERK. Our findings suggest that PTK7 has different oncogenic roles in organs and target tumors. | None |