| The nonreceptor protein tyrosine phosphatase SHP-1 acts as a tumor suppressor in hepatocellular carcinoma | liver, |
| PTPN6 may serve as tumor suppressor gene in ESCC and inhibit esophageal cancer cell proliferation and invasion. The P2 is frequently methylated in esophageal cancer cells and ESCC tissues, and this may be one of the epigenetic mechanisms implicated in PTPN6 silencing in ESCC. | esophageal, |
| STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes. | None |
| Results support the notion that the tumor suppressor effects of SHP1 on NPM-ALK are dependent on its ability to bind to this oncogenic protein. | None |