| Using a genetic screen, study identifies the PTPN12 tyrosine phosphatase as a tumor suppressor in triple-negative breast cancer (TNBC). | breast, |
| Using a genetic screen, study identifies the PTPN12 tyrosine phosphatase as a tumor suppressor in | None |
| These results show that ROS-induced oxidation of PTPN12 accounts for ABL1 phosphorylation in HLRCC-associated PRCC, revealing a novel mechanism for inactivating a tumor suppressor gene product and establishing a direct link between pathologic PTP oxidation and neoplastic disease. | None |
| tumor suppressing gene [review] | None |