Sentence and cancer type
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SentenceCancertype
Proteins of the Bcl2 family regulate the permeability of the mitochondrial membrane for AIF and cytochrome c. This family of structurally related proteins consists of more than twenty members including bcl2 and bcl-x protooncogene products that can block apoptosis and tumor suppressor Bax that on the contrary can induce apoptosis.None
BAX and BAK mediate p53-independent suppression of tumorigenesis. Thus, BAX and BAK function to suppress tumorigenesis, and their deficiency was selected for in vivo. None
A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma. lymphoma,
Epstein-Barr virus encodes a novel homolog of the bcl-2 oncogene that inhibits apoptosis and associates with Bax and Bak. None
Bcl-2 proto-oncogene proteins are expressed in Meissner corpuscles and may play a role in resistance to apoptosis.None
Human Meissner corpuscles express Bcl-2 but not Bax protein. None
Inhibition of Bax activity is crucial for the antiapoptotic function of the human papillomavirus E6 oncoprotein. None
Hypothetical structure of the membrane-associated E5 oncoprotein of human papillomavirus type 16. None
Production of the proto-oncogene BAX does not vary with changing in luteal function in women. None