| Identification of functionally distinct TRAF proinflammatory and phosphatidylinositol 3-kinase/mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (PI3K/MEK) transforming activities emanating from RET/PTC fusion oncoprotein. | None |
| amplification of Raf1, MEK/MAPK oncogenic signaling during tumor growth promotes the genesis of metastatic lesions from primary tumors by activating the mesenchymal epithelial transition. | None |
| Hemopoietic lineage switch: v-raf oncogene converts Emu-myc transgenic B cells into macrophages. | None |
| these data indicate that B-RAF is an important factor in oncogenic C-RAF-mediated tumorigenesis. | None |
| PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility. | None |
| Identification of a transforming activity suppressing sequence in the c-raf oncogene. | None |
| Analysis of c-raf oncogene expression in gastrointestinal tumor cells. | None |
| Data show that when microRNA miR-125b was over-expressed in THP-1 macrophages, the expression of Raf1 proto-oncogene serine/threonine protein kinase (RAF1) was reduced to promote the apoptosis of macrophages. | None |
| Oncogenic NFIA:RAF1 fusion activation of the MAPK pathway is associated with pilocytic astrocytoma. | None |
| Data indicate that Raf-1 proto-oncogene, serine-threonine kinase (RAF1) is a negative regulator of hepatocarcinogenesis. | None |
| Overexpression of ciRS-7 in HCT116 and HT29 cells led to the blocking of miR-7 and resulted in a more aggressive oncogenic phenotype, and ciRS-7 overexpression permitted the inhibition of miR-7 and subsequent activation of EGFR and RAF1 oncogenes | None |
| Expression of human c-raf-1 oncogene proteins in E. coli. | None |
| Identification by a random linker insertion method of a region which suppresses the transforming activity of the raf oncogene. | None |
| Results indicate that proto-oncogene c-RAF (CRAF) function affects postmitotic neural cell differentiation and points to a critical role of CRAF-dependent growth factor signaling pathway in the postmitotic development of adult-born neurons. | None |
| Structure and biological activity of human homologs of the raf/mil oncogene. | None |
| The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene. | None |
| Drosophila melanogaster homologs of the raf oncogene. | None |
| Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. | None |
| findings suggest that the acquisition of a CRAF(P261A) mutation can provide oncogenic properties to cells, and that such cells are sensitive to combined MEK and type II RAF inhibitors | None |
| Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene. | None |