| Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. | breast, |
| Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma. | esophageal, |
| Review loss or abnormality of RAR-b in lung cancer cell lines. It may have tumor suppression function. | lung, |
| Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer. | thyroid, |
| Combined effects of cigarette smoking, gene polymorphisms and methylations of tumor suppressor genes on non small cell lung cancer: a hospital-based case-control study in China. | lung, |
| RARbeta2 acts as a tumor suppressor gene in myelofibrosis with myeloid metaplasia and epigenetic changes are the most significant determinants of RARbeta2 gene activity in these patients. | None |
| (RAR)beta functions as a tumor suppressor gene in various contexts where its absence is associated with tumorigenicity and its presence causes cell cycle arrest. | None |
| RARbeta2 induces a number of tumor suppressor functions and metastasis suppressors | None |
| Down-regulation of the tumor suppressor gene retinoic acid receptor beta2 through the phosphoinositide 3-kinase/Akt signaling pathway. | None |
| Allelic methylation bias of the RARB2 tumor suppressor gene promoter in cancer. | None |
| CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. | None |
| Aberrant methylation of tumor suppressor genes in patients with refractory anemia with ring sideroblasts. | None |
| This work demonstrates a dual role for RARB2 tumor suppression and tumor promotion | None |
| nucleolin plays a coregulatory role in transcriptional regulation of the tumor suppressor RARB2 by COUP-TFII | None |
| DBP(n) are non-toxic to the cells and have a weak overall demethylation effect on genomic DNA. DBP(n) demethylate the promoter regions of the tumor suppressor genes PTEN and RARB. DBP(n) promotes expression of the genes RARB, PTEN, CDKN2A, RUNX3, Apaf-1 and APC silent in the MCF-7 because of the hypermethylation of their promoter regions | None |
| our results defined NR1B2 as a tumor suppressor in KIRC that restricted EMT by the LATS1/2-YAP pathway. | None |
| Our results demonstrate that the majority of RARA-negative acute promyelocytic leukemia (APL) have RARB translocations, thereby forming a novel, distinct subgroup of APL. TBL1XR1-RARB as an oncogenic protein exerts effects similar to those of PML-RARA, underpinning the importance of retinoic acid pathway alterations in the pathogenesis of APL. | leukemia, |