| Expression of a retinoid-inducible tumor suppressor, Tazarotene-inducible gene-3, is decreased in psoriasis and skin cancer. | skin, |
| Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype. | lung,HNSC, |
| Decreased expression of type II tumor suppressor gene RARRES3 in tissues of hepatocellular carcinoma and cholangiocarcinoma. | liver,cholangiocarcinoma, |
| Suppression of the TIG3 tumor suppressor gene in human ovarian carcinomas is mediated via mitogen-activated kinase-dependent and -independent mechanisms. | ovarian, |
| TIG3 tumor suppressor-dependent organelle redistribution and apoptosis in skin cancer cells. | skin, |
| Mutational intratumoral heterogeneity of a putative tumor suppressor gene RARRES3 in colorectal cancers | colorectal, |
| The carboxy-terminal hydrophobic domain of TIG3, a class II tumor suppressor protein, is required for appropriate cellular localization and optimal biological activity. | None |
| A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase. | None |
| The tumor suppressors TIG3, HRASLS2 and H-rev107 are involved in the phospholipid metabolism with different physiological roles. | None |
| Identified the tumor suppressor RARRES3 as a critical target of G9a. Epigenetic silencing of RARRES3 contributed to the tumor-promoting function of G9a | None |
| VS-5584 mediates potent anti-myeloma activity via the upregulation of a class II tumor suppressor gene, RARRES3 and the activation of Bim | None |
| Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene. | None |