| Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor. | retinoblastoma, |
| Aberrant expression of tumor suppressor genes and their association with chimeric oncogenes in pediatric acute lymphoblastic leukemia. | leukemia,pediatric, |
| The retinoblastoma tumor suppressor protein is required for efficient processing and repair of trapped topoisomerase II-DNA-cleavable complexes. | retinoblastoma, |
| data show that E2F1 has potential binding activity to the retinoblastoma control element and a different transcriptional regulation pathway which cooperates with the retinoblastoma tumor suppressor protein | retinoblastoma, |
| Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor. | retinoblastoma, |
| Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase. | retinoblastoma, |
| Our data suggests that RB1 may play a role in colorectal tumorigenesis through functional regulation of the transcript and protein rather than through its tumour suppressor role by gene inactivation. | colorectal, |
| Retinoblastoma tumor suppressor: where cancer meets the cell cycle. | retinoblastoma, |
| Reverse mutational analysis reveals threonine-373 as a potentially sufficient phosphorylation site for inactivation of the retinoblastoma tumor suppressor protein (pRB). | retinoblastoma, |
| The transformation of melanocytes to melanoma cells is characterised by abnormal proliferation due to cell cycle alterations. This occurs through alterations in the retinoblastoma (Rb) and p53 tumour suppressor pathways. | skin,retinoblastoma, |
| Nucleocytoplasmic shuttling of the retinoblastoma tumor suppressor protein via Cdk phosphorylation-dependent nuclear export. | retinoblastoma, |
| The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer. | breast,retinoblastoma, |
| Altered structure and deregulated expression of the tumor suppressor gene retinoblastoma (RB1) in human brain tumors. | brain,retinoblastoma, |
| Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function. | retinoblastoma, |
| The expression level of the tumor suppressor retinoblastoma protein (Rb) influences the antileukemic efficacy of erucylphospho-N,N,N-trimethylpropylammonium (ErPC3). | leukemia,retinoblastoma, |
| RbAp48-mediated transformation of HPV16 is probably because of the regulation by RbAp48 of tumor suppressors retinoblastoma and p53, apoptosis-related enzymes caspase-3 and caspase-8, E6, E7, cyclin D1 (CCND1), and c-MYC. | retinoblastoma, |
| Retinoblastoma tumor suppressor status is a critical determinant of therapeutic response in prostate cancer cells. | prostate,retinoblastoma, |
| Retinoblastoma tumor suppressor deletion in mouse liver enhances diethylnitrosamine-induced tumorigenesis, increased hepatocyte proliferation and compromised genome integrity. | liver,retinoblastoma, |
| Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. | retinoblastoma, |
| The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress. | retinoblastoma, |