| LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription. | None |
| data indicate that attenuation rather than complete inactivation of Rb tumor suppressor gene function, in the context of p53 inhibition, is sufficient to initiate tumorigenesis in this model of islet cell cancer | None |
| RB1 was not implicated, suggesting the participation of another tumor suppressor gene in this region. | None |
| Compensation by tumor suppressor genes during retinal development in mice and humans. | None |
| Results suggest that menin and pRb function in a common pathway of tumor suppression. | None |
| Results identify BNIP3 as a key regulator of hypoxia-induced autophagy and suggest a novel role for the RB tumor suppressor in preventing nonapoptotic cell death by limiting the extent of BNIP3 induction in cells. | None |
| the HPV16 E7-associated cullin 2 ubiquitin ligase complex contributes to aberrant degradation of the pRB tumor suppressor in HPV16 E7-expressing cells. | None |
| Loss of both RB1 tumor suppressor gene alleles initiates quiescent RB1(-/-) retinomas with low level genomic instability and high expression of the senescence-associated proteins p16(INK4a) and p130. | None |
| With tumor suppressor protein p53, RB1 is involved in proteasome inhibition cell senescence. | None |
| These results indicate that PRMT5 overexpression epigenetically alters the transcription of key tumor suppressor genes. | None |
| Proto-oncogene FBI-1 (Pokemon/ZBTB7A) represses transcription of the tumor suppressor Rb gene via binding competition with Sp1 and recruitment of co-repressors. | None |
| The tumor suppressor Pml regulates cell fate in the developing neocortex. | None |
| The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. | None |
| Aurora B determines cellular fate after an aberrant mitosis by directly regulating the Rb tumor suppressor protein. | None |
| contact inhibition imposed by the RB1 pathway performs a tumor suppressor function by preventing cell outgrowth into structures where cells with properties of cancer stem cells can be generated from differentiated somatic cells in advancing cancers. | None |
| study identifies a novel E2F1 gene target and further supports the growing body of evidence that the Rb/E2F1 tumor suppressor pathway is involved in the regulation of the DNA lesion recognition step of nucleotide excision repair. | None |
| Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context. | None |
| Construction of a dual affinity tagged allele of the Rb1 tumor suppressor gene of the mouse is reported. | None |
| Lysine methylation regulates the pRb tumour suppressor protein. | None |
| The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase. | None |