| Data showed that the expression level of RBM3 was higher in human breast cancer tissues compared with adjacent nontumor tissues. A high level of RBM3 was associated with patient lymph node metastasis, high tumor grade and worse overall survival rates. Also, RBM3 upregulated ARPC2 by binding the 3_UTR, contributing to breast cancer progression. These results suggest that RBM3 acts as an oncogene in breast cancer. | breast, |
| Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. | None |
| the RNA stabilizing and translation regulatory protein RBM3 is a novel proto-oncogene that induces transformation when overexpressed and is essential for cells to progress through mitosis. | None |
| Studies showed RBM3 as one of the important cold shock protein with critical roles in rapid cell adaption to the alterations of the environmental stress. Also, RBM3 plays an important role in neuroprotection, anti-apoptotic functions, cell proliferation as well as its function as proto-oncogene.[review] | None |