| A novel germline point mutation, c.2304 G-->T, in codon 768 of the RET proto-oncogene in a patient with medullary thyroid carcinoma. | thyroid, |
| Analysis of mutation of protooncogene RET are presented in patients with thyroid medullary carcinoma | thyroid, |
| [Proto-oncogene RET somatic mutations in medullary thyroid carcinoma]. | thyroid, |
| Papillary thyroid carcinoma in patients with RET proto-oncogene germline mutation. | thyroid, |
| Possible pathogenesis of papillary thyroid carcinoma caused by exon 13 and 14 RET mutations that affect the intracellular domain of ret proto-oncogene protein. | thyroid, |
| High prevalence of RET proto-oncogene activation (RET/PTC) in papillary thyroid carcinomas. | thyroid, |
| A novel Val648Ile substitution in RET protooncogene observed in a Cys634Arg multiple endocrine neoplasia type 2A kindred presenting with an adrenocorticotropin-producing pheochromocytoma. | PCPG, |
| A novel Val648Ile substitution in RET protooncogene observed in a Cys634Arg multiple endocrine neoplasia type 2A kindred presenting with an adrenocorticotropin-producing pheochromocytoma. | PCPG, |
| A founding locus within the RET proto-oncogene may account for a large proportion of apparently sporadic Hirschsprung disease and a subset of cases of sporadic medullary thyroid carcinoma | thyroid, |
| A founding locus within the RET proto-oncogene may account for a large proportion of apparently sporadic Hirschsprung disease and a subset of cases of sporadic medullary thyroid carcinoma. | thyroid, |
| A new therapeutic approach in medullary thyroid cancer treatment: inhibition of oncogenic RET signaling by adenoviral vector-mediated expression of a dominant-negative RET mutant. | thyroid, |
| ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases. | oral |
| Thus, gene rearrangements that generate RET/PTC oncogenes subvert RET function by converting it into a chronically active kinase that is constitutively phosphorylated on tyrosine 1062, Y1062 phosphorylation transmits proapoptotic signals to thyroid cells. | thyroid, |
| RET oncogene mutations in medullary thyroid carcinoma in Mexican families. | thyroid, |
| Expression of RET in follicular cell-derived tumors of the thyroid gland: prevalence and implication of morphological type. | thyroid, |
| Pediatric medullary carcinoma of the thyroid with point mutation of RET proto-oncogene associated with multiple endocrine neoplasia and initially diagnosed by fine-needle aspiration biopsy. | pediatric,thyroid, |
| Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). | thyroid, |
| Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels. | thyroid, |
| Prophylactic thyroidectomy in multiple endocrine neoplasia: the impact of molecular mechanisms of RET proto-oncogene. | thyroid, |
| Cys611Ser mutation in RET proto-oncogene in a kindred with medullary thyroid carcinoma and Hirschsprung s disease. | thyroid, |