| Results showed that TRIM27 was upregulated in colorectal cancer (CRC) tissues, and significantly associated with tumor invasion, metastasis and prognosis. Following TRIM27 inhibition and overexpression in CRC cells, it was found that TRIM27 promoted cell proliferation, possibly via the inhibition of apoptosis and cell cycle regulation. These results suggested that TRIM27 is an oncogenic protein in the progression of CRC. | colorectal, |