Sentence and cancer type
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Sentence
Cancertype
The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: a novel function for the BTB/POZ domain as an autonomous repressing domain.
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The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation.
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Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein.
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The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression.
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Increased expression of the LAZ3 (BCL6) proto-oncogene accompanies murine skeletal myogenesis.
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Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene.
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The proto-oncogene Bc16 inhibits apoptotic cell death in differentiation-induced mouse myogenic cells.
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