| Author reviews the tumor suppressor role of RNase L, proposing that it functions in counteracting prostate cancer by virtue of its ability to degrade RNA, thus initiating a cellular stress response that leads to apoptosis. | prostate, |
| RNASEL may function as a tumor suppressor in prostate cancer. | prostate, |
| RNase L could have a role in cancer biology and evidence of a tumor suppressor function of RNase L has emerged from studies on the genetics of hereditary prostate cancer [review] | prostate, |
| Plays role in senescence that may contribute to its tumor suppressive function and to the enhanced longevity of RNase-L-deficient mice. | None |
| support a model in which the RNase-L-mediated degradation of ribosomal protein mRNAs inhibits translation, and may contribute to its antiproliferative, senescence inducing and tumor suppressor activities. | None |