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Cancertype
In this study silencing BACH2 in mantle cell lymphoma cells resulted in increased proliferation and enhanced tumor dispersal in hypoxic microenvironments, suggesting a tumor suppressor-like role of BACH2.
lymphoma,
Data show that B-cell tumour suppressor BTB and CNC homology 2 (Bach2) was significantly downregulated by the loss of NF-kappaB subunit proto-oncogene protein c-rel (c-Rel) .
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