| GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. | breast, |
| a decrease in GAS5 expression is associated with Renal cell carcinoma genesis and progression and overexpression of GAS5 can act as a tumor suppressor for Renal cell carcinoma | kidney, |
| Gas5 Exerts Tumor-suppressive Functions in Human Glioma Cells by Targeting miR-222 | glioma, |
| GAS5 acts as a tumor suppressor in HCCs. | liver, |
| GAS5 acts as an tumor suppressor lncRNA in endometrial cancer. Through inhibiting the expression of miR-103, GAS5 significantly enhanced the expression of PTEN to promote cancer cell apoptosis | endometrial, |
| Long non?coding RNA?GAS5 acts as a tumor suppressor in bladder transitional cell carcinoma via regulation of chemokine (C?C motif) ligand 1 expression | bladder, |
| In this review, we will summarize the current knowledge about LncRNA GAS5, a recently identified tumor suppressor involved in several cancers, like breast cancer, prostate cancer, lung cancer, and colorectal cancer | colorectal,breast,prostate,lung, |
| Study shows that GAS5 may function as a tumor suppressor by inhibiting melanoma cell invasiveness via the regulation of MMP2 expression and its activity. | skin, |
| Discovered a novel long noncoding RNA termed GAS5-AS1 as a tumor suppressor in non-small cell lung cancer (NSCLC). The expression of GAS5-AS1 in NSCLC tumors was much lower than that in the adjacent normal lung tissues. The reduced GAS5-AS1 was significantly correlated with larger tumors, higher TNM stages, and lymph node metastasis in NSCLC patients. | lung, |
| Long Noncoding RNA GAS5, Which Acts as a Tumor Suppressor via microRNA 21, Regulates Cisplatin Resistance Expression in Cervical Cancer | cervical, |
| our findings suggest that GAS5 is a tumor suppressor in human gliomas that acts in part by repressing miR-18a-5p. | glioma, |
| The tumor suppressor lncRNA GAS5 was significantly under-expressed in the three types of cancer, renal cell carcinoma (RCC), glioblastoma (GB), and hepatocellular carcinoma (HCC) [0.08 (0.006-0.38) in RCC, p <0.001; 0.10 (0.003-0.89) in GB, p < 0.001; and 0.12 (0.015-0.74) in HCC, p < 0.001]. | liver,glioblastoma,kidney, |
| Long Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21 | laryngeal, |
| Erratum: Long Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21 [Corrigendum] | laryngeal, |
| GAS5 functioned as a tumor suppressor role in HCC through regulation of miR-21-PTEN singling pathway. | liver, |
| Long non?coding RNA growth arrest?specific 5 (GAS5) acts as a tumor suppressor by promoting autophagy in breast cancer | breast, |
| Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. | None |
| In this review, author summarized the gene as tumor suppressor in table 2. | None |
| Together, these results suggest that GAS5 functions as a tumor suppressor gene in ESCC and is regulated by miR-196a involved in RISC. | None |
| Novel Tumor Suppressor lncRNA Growth Arrest-Specific 5 (GAS5) In Human Cancer | None |