| results confirm the role of CSDM1 as a tumor suppressor gene in melanoma cells; study also found that CSMD1 can interact with Smad3, activate Smad1, Smad2, and Smad3, and increase the expression of Smad4 | skin, |
| CSMD1 alterations can correlate with earlier clinical presentation in colorectal tumors, thus further implicating CSMD1 as a tumor suppressor gene. | colorectal, |
| Study provide experimental evidence for the role of CSMD1 as a tumor suppressor in vitro and in vivo in the progression of breast cancer. Results revealed that expression of CSMD1 significantly reduced cell motility and migration, adhesion and invasion, as well as the tumorigenic and signaling potential of human breast cancer cells. | breast, |
| Rare frameshift mutations of putative tumor suppressor genes CSMD1 and SLX4 in colorectal cancers | colorectal, |